SOLBAN - Niacinamida (Vit B3) Transdermal -  (rejuvenecimiento y protección de la piel)

SOLBAN - Niacinamida (Vit B3) Transdermal - (rejuvenecimiento y protección de la piel)

Precio habitual
$19.99
Precio de oferta
$19.99

Cafeína líquida, aspirina y niacinamida (vitamina B3) transdermal para la piel. Todos ingredientes demostrados científicamente efectivos para este propósito (ver lista de referencias más abajo).

Para la gente interesada en mejorar la salud de su piel, o gestionar problemas como la pérdida del cabello, las arrugas, celulitis, dermatitis o simplemente protegerse de los daños de la sobreexposición al sol.

Este suplemento es de uso tópico y consiste en una solución de agua/etanol que contiene niacinamida (vitamina B3), cafeína y aspirina. La combinación de cafeína y niacinamida tiene un efecto protector del sol según la literatura científica.

SolBan está disponible como disolución al 20 % alcohol (ethanol) en un bote de cristal de 2 onzas (en spray). Es un producto para uso tópico.

INFORMACIÓN DEL PRODUCTO
Dosis: 5 sprays (aprox 1ml)
Dosis por contenedor: 60
Cada dosis contiene:

Niacinamida / Nicotinamida - 40 mg
Cafeina - 10 mg
Aspirina - 10 mg
Ácido succínico - 10 mg

Otros ingredientes: agua, etanol

Modo de administración: aplicar el spray sobre la zona afectada hasta que tenga una fina capa, dejarlo secar (sin frotar).

NOTA SOBRE EL ENVÍO
Este suplemento se envía desde los EEUU por medio de USPS. Tarifa plana de $13 con un tiempo medio de 7-10 días. El envío es hasta un peso de 250 gramos (hasta 5 botellas de SOLBAN o mezcla de otros suplementos de la tienda). Por ello, se recomienda pedir más de una botella en el mismo envío.

 

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INFORMACIÓN CIENTÍFICA Y ESTUDIOS
El ácido succínico, también presente en el producto, aumenta el ATP y mejora el crecimiento del cabello en aquellos con problemas de alopecia (según estudios):

Effect of the glyceride of pentadecanoic acid on energy metabolism in hair follicles
"...The effect of the glyceride of pentadecanoic acid (PDG) in treating male pattern alopecia has already been confirmed in a double blind controlled clinical test. In order to study the mechanism of the hair growing effect of PDG, ATP levels were measured in the hair follicles of rabbits. The ATP levels in telogen hair follicles increased remarkably with the application of PDG. To examine this effect, the metabolic properties of pentadecanoic acid (PDA) were investigated using the mitochondrial fraction prepared from guinea-pig hair follicles. It was shown that PDA could be metabolized in hair follicles, and succinic acid, which was formed in the degradation process of PDA, had a remarkable ATP producing ability. These results suggest that the hair growing effect of PDG depends on the efficient supply of energy to hair follicles, and this mechanism seems to be derived from the metabolic property of the odd numbered carbon fatty acid, PDA."


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ESTUDIOS

1. NIACINAMIDA (vitamina B3)
Nicotinic acid/niacinamide and the skin. - PubMed - NCBI
Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. - PubMed - NCBI
A review of nicotinamide: treatment of skin diseases and potential side effects. - PubMed - NCBI
Nicotinic acid/niacinamide and the skin. - PubMed - NCBI
Nicotinamide and the skin. - PubMed - NCBI
Nicotinamide - biologic actions of an emerging cosmetic ingredient. - PubMed - NCBI

1.1 Hyperpigmentation and Skin Aging (niacinamide)
Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. - PubMed - NCBI
A review of nicotinamide: treatment of skin diseases and potential side effects. - PubMed - NCBI
Niacinamide - mechanisms of action and its topical use in dermatology. - PubMed - NCBI
Niacinamide: A B vitamin that improves aging facial skin appearance. - PubMed - NCBI
The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparativ... - PubMed - NCBI
Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study. - PubMed - NCBI
Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamin... - PubMed - NCBI
Reduction in facial hyperpigmentation after treatment with a combination of topical niacinamide and tranexamic acid: a randomized, double-blind, ve... - PubMed - NCBI
A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. - PubMed - NCBI
The effect of 2% niacinamide on facial sebum production. - PubMed - NCBI
Moisturizing effects of topical nicotinamide on atopic dry skin. - PubMed - NCBI

1.2 UV Damage (niacinamide)
Nicotinamide-containing sunscreens for use in Australasian countries and cancer-provoking conditions. - PubMed - NCBI
Topical nicotinamide modulates cellular energy metabolism and provides broad-spectrum protection against ultraviolet radiation-induced immunosuppre... - PubMed - NCBI
Ultraviolet A radiation: its role in immunosuppression and carcinogenesis. - PubMed - NCBI
Nicotinamide enhances repair of ultraviolet radiation-induced DNA damage in primary melanocytes. - PubMed - NCBI
Nicotinamide reduces photodynamic therapy-induced immunosuppression in humans. - PubMed - NCBI
Nicotinamide enhances repair of ultraviolet radiation-induced DNA damage in human keratinocytes and ex vivo skin. - PubMed - NCBI
Nicotinamide downregulates gene expression of interleukin-6, interleukin-10, monocyte chemoattractant protein-1, and tumour necrosis factor-α gene ... - PubMed - NCBI
Oral and systemic photoprotection. - PubMed - NCBI
Photoprotective effects of nicotinamide. - PubMed - NCBI
Nicotinamide prevents ultraviolet radiation-induced cellular energy loss. - PubMed - NCBI
Oral nicotinamide protects against ultraviolet radiation-induced immunosuppression in humans. - PubMed - NCBI
UV radiation-induced immunosuppression is greater in men and prevented by topical nicotinamide. - PubMed - NCBI
[The intervention of nicotinamide on skin melanocyte's cell proliferation after UVA (365 nm) exposed.]. - PubMed - NCBI
Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide. - PubMed - NCBI
Effects of nicotinamide on mouse skin tumor development and its mode of action. - PubMed - NCBI
Nicotinamide and nicotinamide analogues as antitumor promoters in mouse skin. - PubMed - NCBI


2. CAFEÍNA
Follicular penetration of topically applied caffeine via a shampoo formulation. - PubMed - NCBI
The role of hair follicles in the percutaneous absorption of caffeine. - PubMed - NCBI
Topical delivery of caffeine from some commercial formulations. - PubMed - NCBI

2.1 Sunscreen effects (caffeine)
Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 ... - PubMed - NCBI

2.2 Skin cancer (caffeine)
Topical applications of caffeine or (−)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice
A novel topical targeting system of caffeine microemulsion for inhibiting UVB-induced skin tumor: characterization, optimization, and evaluation. - PubMed - NCBI
Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated mice. - PubMed - NCBI
Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB treated mice
Effect of caffeine on UVB-induced carcinogenesis, apoptosis, and the elimination of UVB-induced patches of p53 mutant epidermal cells in SKH-1 mice. - PubMed - NCBI
Protection from photodamage by topical application of caffeine after ultraviolet irradiation. - PubMed - NCBI
Inhibitory effects of tea and caffeine on UV-induced carcinogenesis: relationship to enhanced apoptosis and decreased tissue fat. - PubMed - NCBI
Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in mouse skin. - PubMed - NCBI

2.3 Other skin conditions (caffeine)
The effect of topically applied aspirin on localized circumscribed neurodermatitis. - PubMed - NCBI
Topical treatment of cutaneous herpes simplex virus-1 infection in mice with a specially formulated caffeine gel (Cafon). - PubMed - NCBI
Effect of caffeine and testosterone on the proliferation of human hair follicles in vitro. - PubMed - NCBI
Histopathological evaluation of caffeine-loaded solid lipid nanoparticles in efficient treatment of cellulite. - PubMed - NCBI
Role of Caffeine in the Management of Androgenetic Alopecia
Pharmacokinetics for topically applied caffeine in the rat. - PubMed - NCBI
Effectiveness of topical caffeine in cataract prevention: studies with galactose cataract. - PubMed - NCBI
Evaluation of the efficacy of topical caffeine in the treatment of psoriasis vulgaris. - PubMed - NCBI
Caffeine inhibits paresthesia induced by herpes simplex virus through action on primary sensory neurons in rats. - PubMed - NCBI


3. ASPIRINA
Combined patch containing salicylic acid and nicotinamide: role of drug interaction. - PubMed - NCBI
Design of a transdermal delivery system for aspirin as an antithrombotic drug. - PubMed - NCBI
Transdermal modification of platelet function. A dermal aspirin preparation selectively inhibits platelet cyclooxygenase and preserves prostacyclin... - PubMed - NCBI
Topically applied aspirin decreases histamine-induced wheal and flare reactions in normal and SLS-inflamed skin, but does not decrease itch. A rand... - PubMed - NCBI
Topically applied aspirin rapidly decreases histamine-induced itch. - PubMed - NCBI